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First evidence of geometrical patterns and defined distances of biomolecules as fundamental parameters to regulate receptor binding and cell signaling have emerged recently. Here, we demonstrate the ...

kDepartment of Cell and Chemical Biology, Leiden University Medical Center, Leiden, Netherlands lDepartment of Biomedical Data Sciences, Section Molecular Epidemiology, Leiden University Medical ...

Journal of Nuclear Medicine May 2025, jnumed.124.269444; DOI: https://doi.org/10.2967/jnumed.124.269444 ...

Now, researchers have taken a decisive step towards understanding how. “This single receptor is responsible for our insatiable, never-ending attraction to sugar,” says Columbia neuroscientist ...

Citation: Discovery of dopamine receptors in overlooked brain region sheds light on complex circuitry for anxiety and depression (2025, May 7) retrieved 25 May 2025 from https://medicalxpress.com ...

Researchers have discovered distinct roles for two dopamine receptors located on nerve cells within the portion of the brain that controls approach vs. avoidance behavior. Mount Sinai researchers ...

Preclinical data have shown that cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors can inhibit tumour growth and act synergistically with oestrogen receptor antagonists to overcome endocrine therapy ...

Limited data exist on the association of glucagon‐like peptide 1 receptor agonists (GLP‐1RAs) with the risk of venous thromboembolism. This meta‐analysis aimed to investigate the association between ...