There was no history of liver disease, acute intermittent porphyria, pyruvate carboxylase deficiency, fatty acid oxidation defects, primary carnitine deficiency, palmitoyl transferase I or II ...

In their paper, the authors explained further, “In healthy mitochondria, PINK1 is translocated across the mitochondrial outer membrane (MOM) via the translocase of the outer membrane (TOM ...

Out popped a 750 kDa supercomplex, containing not just multiple translocase components but also VDAC, acylglycerol kinase and a handful of chaperones—all bound together with PINK1 itself. Scaling up ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Most cellular proteins require targeting to a ...

Cerebral blood flow, oxygen, glucose, lactate, and pyruvate metabolism were measured in 13 subjects with completed stroke. Cerebral blood flow and oxygen consumption were reduced, glucose consumption ...

The characterization of a single protein function is associated with an enumeration of different features. Some of these features are the subcellular localization of the protein, its interaction with ...

Croucher Institute for Environmental Sciences, Department of Biology, Hong Kong Baptist University, Hong Kong SAR ...