More information: Shubhangi Agarwal et al, Ball-and-chain inactivation of a human large conductance calcium-activated ...

In a widely cited study in 2020, Dr. Nimigean and colleagues revealed this ball-and-chain structure in a simpler potassium channel called MthK, an evolutionarily distant relative of BK channels ...

The purpose of protein synthesis is simply to create a polypeptide -- a protein made out of a chain of amino acids. In a hair follicle cell, a protein called keratin is made. Lots of it.

Protein function predictions are bioinformatic methods (i.e. involving computation using software) that aim to predict the function of a protein. Protein function analyses use protein sequences ...

The sequence of amino acids in the chain determines how the chain will fold up to make the protein, so different proteins have different three-dimensional shapes. The three-dimensional shape of a ...

Study establishes 'ball and chain' mechanism inactivates key mammalian ion channel Date: March 4, 2025 Source: Weill Cornell Medicine Summary: A new study has unveiled a precise picture of how an ...

A new study has unveiled a precise picture of how an ion channel found in most mammalian cells regulates its own function with a "ball-and-chain" channel-plugging mechanism, according to ...