Key points A 47-year-old French-speaking woman of African descent presented to the emergency department with a 1-week history of severe foot pain and difficulty walking. For the preceding 2 months she ...

Conclusions: Achieving rapid remission after LLDAS attainment remains challenging for most SLE patients, mainly due to difficulties in reducing prednisone dosage to ≤5 mg/day. Systemic lupus ...

At discharge, the patient was asymptomatic, the laboratory tests were normal as reported in Table 1, and the therapy included prednisone at a dosage of 50 mg per day, with plans for gradual tapering .

A prednisone taper gradually reduces your corticosteroid dose over days, weeks, or months to prevent prednisone withdrawal. Stopping prednisone abruptly can lead to adrenal insufficiency ...

In patients with lupus, those taking prednisone or demonstrating active disease and a more recent initial episode are more likely to have pericarditis recurrence. Overall recurrence was lower than ...

Anifrolumab can substantially lower the risk for long-term organ damage progression in patients with moderate to severe ...

May 23, 2024 — Treatment of autoimmune diseases like lupus has long relied on steroids to knock down the immune system, but more targeted therapies are currently undergoing clinical trials.

As a result, there is no evidence from controlled studies on the efficacy of different initial doses or drug tapering. The only controlled study suggests that initial prednisone doses ≤ 10 mg is ...

A prednisone taper gradually reduces your corticosteroid dose over days, weeks, or months to prevent prednisone withdrawal. Stopping prednisone abruptly can lead to adrenal insufficiency, which causes ...

Researchers performed a post hoc analysis of the ADVOCATE trial (ClinicalTrials.gov Identifier: NCT02994927) to evaluate the efficacy and safety of avacopan vs a prednisone taper among patients with ...