and irritable myopathy (18%). Jo-1 antibodies were not found in the five patients tested. The distinctive feature of muscle biopsies was perimysial pathology (92%), including acid phosphatase positive ...

A predominant myositis pattern was characterized by necrotizing fibers and vacuolar changes in muscle histology, Keywords: Anti-Ku antibody, Skeletal muscle pathology, Autophagy, Myositis, Autoimmun ...

Inflammatory myopathy: This has the features similar to those seen in ... Most patients respond to glucocorticoid therapy, and the overall prognosis is favourable. The pathology is almost always seen ...

In the clinical trial (NCT05859997), three patients with therapy-resistant autoimmune diseases—including immune-mediated necrotizing myopathy (IMNM ... which contribute to the pathology of SSc Scl70+ ...

Results of an autopsy-based study revealed that sudden cardiac death and multiorgan pathology may be more closely linked to SSc than previously thought.

Among 47 patients with any of several forms of idiopathic inflammatory myositis (IIM) who took efgartigimod (Vyvgart Hytrulo) ...

This paper reports on a correlation between diminished cardiolipin content and the severity of steatohepatitis in human subjects. This is supported further by experimental evidence from mice in which ...

Critical illness polyneuropathy (CIP) and critical illness myopathy (CIM) are major complications that occur in severely ill patients who require intensive care treatment. CIP and CIM affect the ...

Please provide your email address to receive an email when new articles are posted on . Women with axial spondyloarthritis demonstrated lower response vs. men to IL-17A and TNF inhibitors. Future ...

The pathogenesis of tendinopathy and the primary biological change in the tendon that precipitates pathology have generated several pathoaetiological models in the literature. The continuum model of ...