New research by Sumeda Nandadasa, Ph.D., reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, ...

We previously reported the discovery of pyrimido-pyrrolo-quinoxalinedione (PPQ) inhibitors of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel and showed their efficacy ...

Background The gut microbiota has been linked to non-communicable diseases, including chronic kidney disease (CKD). However, the relationships between gut microbiome composition changes, uraemic ...

MONDAY, June 9, 2025 (HealthDay News) — Prompt treatment with a drug combo can effectively manage chronic kidney disease in people with type 2 diabetes, a new clinical trial shows.

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Otsuka's experimental therapy for a potentially life-threatening kidney disease more than halved severe levels of protein in the urine of patients, intensifying the battle for an effective new ...

Blake Shore was born with a rare genetic disease and also has polycystic kidney disease. Because of the disease, he now needs a new kidney. Posted 6/5/2025, 4:08:11 AM Updated 6/6/2025, 10:01:08 PM ...

Autosomal dominant polycystic kidney disease (ADPKD) causes progressive cyst formation and renal failure. Tank-binding kinase 1 (TBK1), a key regulator of inflammation, represents a promising target ...

Vafseo ® (vadadustat) was approved by the U.S. Food and Drug Administration in March 2024 for the treatment of anemia due to chronic kidney disease in adults who have been receiving dialysis for ...

Transition from acute kidney injury to chronic kidney disease: mechanisms, models, and biomarkers. American journal of physiology. Renal physiology , 327 (5), F788–F805.

On May 23, the WHO recognized kidney disease as a global health threat and urged member states to take steps to promote kidney health and strengthen prevention and treatment efforts, according to ...

Kidney disease is an example of the damage that prolonged, incessant heat can do to the body, says Ollie Jay, a heat physiologist at the University of Sydney in Australia.