When testing the utility of these methodologies in cultured hepatocytes, we discovered that the presence of baculovirus disrupts the phenobarbital ... induction of specific cytochrome P450 ...

In this case series, the authors focused on analyzing the interaction between first generation anticonvulsants (ie, phenytoin, carbamazepine, phenobarbital), which are potent inducers of CYP450 ...

Phenobarbital causes a marked proliferation of the smooth-surfaced membranes of the endoplasmic reticulum in the liver cells. And, like many other compounds, it is an inducer of drug-metabolizing ...

phenobarbital, phenytoin, primidone, oxcarbazepine, rifampin, rifapentine, or St. John's wort in the previous two weeks. Let your doctor if you stop taking any of the medicines or if you condition ...

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment ...

Although the results of the present study strongly suggest that the lowering of serum bilirubin concentration by phenobarbital in the hyperbilirubinemic infant was due to induction of a ...

The products of the cytochrome P450 (CYP) genes play an ... mediates the well studied induction of CYP2B10 gene expression by phenobarbital (PB) and 1, 4-bis-[2-(3, 5,-dichloropyridyloxy)] benzene ...

It is now recognized that reduced 25-hydroxyvitamin D levels may result from the up-regulation of the hepatic cytochrome P450 enzymes by anticonvulsant inducers, such as phenobarbital, phenytoin, and ...