aDepartment of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada bDepartment of Pathology and Laboratory Medicine, University of British Columbia, ...

SAILING is a Phase III, randomized, double-blind, double-placebo, multicenter, parallel-group, noninferiority study in antiretroviral treatment-experienced, integrase inhibitor-naive, HIV-1 ...

SpacePHARER is a modular toolkit for sensitive phage-host interaction identification using CRISPR spacers. SpacePHARER adapts the fast homology search capabilities of MMseqs2 to sensitively query ...

Gilead Sciences Inc. has divulged bridged tricyclic carbamoylpyridone prodrugs acting as HIV integrase inhibitors reported to be useful for the treatment of HIV infection.

aeruginosa—one of the most prevalent infection-causing bacteria in cystic fibrosis—and evidence of phage-resistant bacteria having reduced pathogenicity in the nine adults treated with this ...

The newly preferred nPEP regimens include three drugs: an HIV integrase inhibitor, either bictegravir or dolutegravir, together with 2 nucleoside analog reverse transcriptase inhibitors (NRTIs ...

Cellular Signaling Laboratory, International Research Center for Sensory Biology and Technology of MOST, Key Laboratory of Molecular Biophysics of MOE, College of Life Science and Technology, Huazhong ...