From the Department of Cardiology and Angiology I, University Heart Center Freiburg, Germany (D.W.) Faculty of Medicine, University of Freiburg, Germany (D.W.) K. Ley has received research funding for ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. In response to infections, naive CD8 T cells ...

Mol Cancer Ther (2025) 24 (4): 497–510. Murine double minute 2 (MDM2) is an E3 ligase that inhibits the tumor suppressor protein p53. Clinical trials employing small-molecule MDM2/p53 interaction ...

5Department of Microbiology, Immunology and Tropical Medicine, The George Washington University Cancer Center, The George Washington University School of Medicine and Health Sciences, Washington, ...

MANILA, Philippines — Motorists should prepare for another round of fuel price hike starting Tuesday, April 1. Oil companies will raise gasoline prices by P1.40 per liter, and kerosene and ...

PALO ALTO, Calif., March 27, 2025 (GLOBE NEWSWIRE) -- BridgeBio Pharma, Inc. (Nasdaq: BBIO) (“BridgeBio” or the “Company”), a new type of biopharmaceutical company focused on genetic ...

The team observed that the HFSCs were still alive for some time, but soon became overworked – which triggered a stress signal (P53) that ultimately killed the cells. In 2022, another team of ...

Optogenetic tools enable very precise spatiotemporal control of the signaling pathway. The authors developed an optimized light-regulated PKC epsilon, Opto-PKCepsilon using AlphaFold for rational ...

Chemical Biology Program, Department of Pharmacology and Toxicology, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States ...

Department of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003, United States Molecular and Cellular Biology Program, University of Massachusetts, Amherst, Massachusetts 01003, ...