A dangerous police chase through several cities in Orange County ended with a crash and a deadly police shooting.

The second owner of a curio shop in Orange City was arrested and accused of selling human bones on her shop's website and Facebook Marketplace, police said on Wednesday. Ashley Lelesi, 32 ...

Meredith Starkenburg responds to the polarizing political moments in Orange County — and the politics driving the fight over ...

Doctors at City of Hope Orange County say there's a great need for increased cancer research and access to treatment in O.C., ...

An Orange County Superior Court judge is siding with Huntington Beach on Tuesday in its legal tussle with the state over a ...

City of Hope is on its way to opening Orange County’s first hospital dedicated exclusively to cancer care around the end of ...