References [1] Lipophilic Nucleoside Triphosphate Prodrugs of Anti‐HIV Active Nucleoside Analogs as Potential Antiviral Compounds. Advanced Science (2023). [2] A phase I open-label, dose ...

PRESENT knowledge of intermediary metabolism is to a large degree linked to the concept of energy transfer by so-called ‘energy-rich’ compounds1 of which adenosine triphosphate is one of the ...

Edited* by Edwin W. Taylor, Northwestern University Feinberg School of Medicine, Chicago, IL, and approved July 5, 2011 (received for review September 15, 2010) Here we present a mechanism by which ...

The expeditious convergent synthesis of the potent human purine nucleoside phosphorylase inhibitor DADMe-Immucillin-G (3) was achieved via the Mannich reaction. The Mannich chemistry of a series of ...

The role of protein dynamics on different time scales in enzyme catalysis remains an area of active debate. The connection between enzyme dynamics on the femtosecond time scale and transition state ...