The NOTCH family includes four receptors (NOTCH1-4) and interacts with ligands like Delta-like (DLL) and Jagged (JAG). NOTCH signaling can be canonical or noncanonical. Canonical signaling ...

The NOTCH family includes four receptors (NOTCH1-4) and interacts with ligands like Delta-like (DLL) and Jagged (JAG). NOTCH signaling can be canonical or noncanonical. Canonical signaling ...

The Notch family of transmembrane receptors comprises four members, with roles in the regulation of cell fate and growth. Following ligand binding, a conformational change in the receptor negative ...

New conditionally replicative adenovirus vector with synNotch receptor gene for MIBC treatment March 25, 2025 The MIBC subtype accounts for around 25% of all BC cases, with a significant proportion of ...