C&EN3d
Linker Design Principles for the Precision Targeting of Oncogenic G-Quadruplex DNA with G4-Ligand-Conjugated Oligonucleotides
All MST experiments were performed on a Monolith NT.115 (Nanotemper, Germany) instrument and performed in MST buffer. The G4 DNA concentration was kept constant at 10–20 nM, to which GL-Os were ...
eLife2d
Structure-Guided Loop Grafting Improves Expression and Stability of Influenza Neuraminidase for Vaccine Development
The thermal stability and unfolding of NA proteins were measured using the nanoDSF (differential scanning fluorimetry) technique on a Prometheus Panta instrument (Nanotemper). NanoDSF monitors changes ...
The EMBO Journal23d
Proton conductance by human uncoupling protein 1 is inhibited by purine and pyrimidine nucleotides
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Uncoupling protein 1 (UCP1, SLC25A7) is ...
C&EN27d
Dynamic Assembly of Pentamer-Based Protein Nanotubes
Departments of Mathematics, University of York, York YO10 5DD, U.K. Departments of Mathematics, University of York, York YO10 5DD, U.K. Department of Biology ...