† Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, United States ‡ Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States Article Views ...

This work not only extended the application of aptamers to screen small-molecule inhibitors for the undruggable lung cancers, but more importantly provided a new strategy to develop protein knockdown ...

One route has been the identification of antimicrobial chemical weaponry in Nature as small-molecule natural products were observed to have clinically useful antibacterial activity. Among these ...

Documentation is available at https://posebusters.readthedocs.io. For more information about the tests and for a study using PoseBusters to compare docking methods, refer to our paper or preprint: ...

Breakthroughs in science tend to start with a small step. For scientists in Australia, a small step might offer new hope to patients who are suffering from neurodegenerative diseases such as ...

A ceremony marking the start of construction on AstraZeneca's new small molecule drug factory is held in Wuxi, East China's Jiangsu province, on May 8. [Photo provided to chinadaily.com.cn ...

Punishing conditions in the clouds of Venus could be home to a DNA-like molecule capable of forming genes in life very different to that on Earth, according to a new study. Long thought to be ...

For small molecule drugs (chemical compounds that are usually pills, e.g. empagliflozin [Jardiance]), prices are negotiated at year 7 and take effect 9 years after FDA approval. For biologics ...

Peptone is a biotechnology company developing novel first-in-class small molecule therapeutics targeting intrinsically disordered proteins (IDPs) to treat diseases through a pioneering experimental ...

Punishing conditions in the clouds of Venus could be home to a DNA-like molecule capable of forming genes in life very different to that on Earth, according to a new study. Long thought to be hostile ...

A molecule designed to activate iron locked up in organelles called lysosomes and thereby induce cell death might offer a way to tackle treatment-resistant cancer. Building on the foundation ...

Norwegian artist and producer Ora The Molecule is in the US this month for a few select shows, playing Seattle and Los Angeles before heading to Brooklyn for a DJ set at Nightmoves on May 22.