These findings suggest that people with gum disease, especially those infected with P. gingivalis producing gingipain, may be ...

LC3II is integrated into the nascent phagosome membrane and acts as a marker that facilitates phagophore fusion with lysosomes (Hale et al., 2012). Together, these two systems help complete phagosome ...

which is an inhibitor of autophagy by raising lysosomal pH and therefore preventing autophagosome–lysosome fusion.40 Similarly, many pharmaceuticals approved in the European Union and USA, and in ...

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The biotech is focusing on precision, small-molecule medicines that work via a process known as cellular clearance by activating the lysosome, sometimes referred to as the cell’s recycling and ...

Diabetic retinopathy (DR), a leading cause of vision loss and blindness worldwide, is caused by retinal neurovascular unit dysfunction, and its cellular pathology involves at least nine kinds of ...