General transcription factor IIIC subunit 2 (GTF3C2) is one of the polymerase III transcription-related factors. Previous studies have revealed that ...

Mar. 13, 2025 — When mothers eat a diet high in fat and sugars, their unborn babies can develop liver stress that continues into early life. A new study sheds light on changes to the fetus's ...

PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...

The authors have generated important resources such as a reference dataset of early primate development by utilizing single-cell transcriptomic technology together with induced pluripotent stem cells ...

Hepatocytes, as the most abundant cell type in liver, are a potent source of fibrogenic lipid peroxides in inflammatory liver diseases. Platelets are a potent source of growth factors, and are ...

Age-related increases in translational errors were observed in muscle and brain, but not in liver, highlighting organ-dependent declines in translation fidelity as a possible contributor to aging.

the authors show that low levels of VDAC2 and Bak in hepatocyte mitochondria make them resistant to cell death induced by truncated Bid (tBid), while increased VDAC2 and Bak in liver cancer cells ...