A common medication already used for autoimmune diseases such as rheumatoid arthritis is effective for patients with giant ...

Significant data exists to suggest that dual leucine zipper kinase (DLK, MAP3K12) is a conserved regulator of neuronal degeneration following neuronal injury and in chronic neurodegenerative disease.

Acute myocarditis—sudden inflammation of the heart—causes mild symptoms in most cases, but about 10% of acute myocarditis ...

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For children with severe Crohn disease, upadacitinib offers an effective induction therapy, but its benefits must be carefully weighed against potential adverse events.

Deucravacitinib is a first-in-class, oral, selective, allosteric tyrosine kinase 2 (TYK2) inhibitor approved in multiple countries for the treatment of adults with moderate to severe plaque ...

Citation: Su B, Luan Z-L, Liu H, Tuomilehto J and Ji X (2025) Janus kinase and signal transducer and activator of transcription inhibitors in type 1 diabetes and immune checkpoint–related diabetes: ...

Janus kinase inhibitor monotherapy was linked to a slightly higher GIP incidence (1.46 per 1000 PYs) compared against JAK inhibitors with background csDMARD use (1.00 per 1000 PYs). Study limitations ...

Methods The aim of this predefined interim analysis was to report baseline characteristics along with early (3-month) descriptive and comparative real-world effectiveness in patients with PsA ...

The ACG has released new clinical guidelines for the management of ulcerative colitis and Crohn’s disease in adult patients.The guidelines, published in The American Journal of Gastroenterology ...

Supported by a talented team committed to making a difference for patients worldwide, the Company was founded in 2014 and is based in Lyon, France. As a pioneer, MaaT Pharma is leading the way in ...