The ACG has released new clinical guidelines for the management of ulcerative colitis and Crohn’s disease in adult patients.The guidelines, published in The American Journal of Gastroenterology, ...

For children with severe Crohn disease, upadacitinib offers an effective induction therapy, but its benefits must be carefully weighed against potential adverse events.

Janus kinase (JAK) inhibitors are not associated with an increased risk for gastrointestinal perforation (GIP) among patients with rheumatoid arthritis (RA), according to study results published in ...

Switching to a second-line Janus kinase (JAK) inhibitor resulted in steroid-free clinical remission in about half of the patients with active ulcerative colitis (UC) after induction; compared with ...

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NS-229 is an investigational selective Janus kinase 1 (JAK1) inhibitor designed to prevent tissue damage caused by EGPA by suppressing immune cell activation. A global, randomized, double-blind ...

Janus kinase inhibitors — also known as JAKs — are commonly prescribed for autoimmune diseases like rheumatoid arthritis. You might know them by their brand names, such as Xeljanz, Olumiant ...

Although the medications, called Janus kinase (JAK) inhibitors, don’t cure alopecia areata—hair falls out again if patients stop taking it—they are revolutionizing treatment and making the ...