A multidisciplinary team led by Professor Li Yulong from the School of Life Sciences at Peking University has developed a far ...

Semaglutide, a synthetic analog of glucagon-like peptide-1 (GLP-1), has garnered attention for its intriguing properties and potential implications in various r ...

By combining HypnoS with in vivo wide-field imaging techniques, the researchers mapped the dynamic changes of intracellular adenosine during epileptic seizures in live mouse brains, with the entire ...

Intracellular signaling. Intracellular signaling encompasses two broad areas, Ca 2+ signaling evoked or modulated by ANs, and signaling by the intracellular second messenger 3’,5’-cyclic adenosine ...

Design Isolated pancreatic acinar cells were exposed to secretagogues, uncaged IP 3 or toxins that induce AP and effects of xanthines, non-xanthine phosphodiesterase (PDE) inhibitors and cyclic ...

The activation of this receptor increases levels of the intracellular signaling molecules, cyclic adenosine monophosphate (cAMP) and inositol triphosphate (IP3). Both cAMP and IP3 eventually ...

The signal transduction process is one by which an external signal is detected by the cell and converted into cellular responsive actions leading to changes in secondary messengers, such as cAMP ...

By Pooja Toshniwal Paharia In a recent review published in Cell Metabolism , researchers present the role of cyclic fasting and fasting-mimicking diets (FMD) in cancer therapy. Study: Cyclic ...

Phosphodiesterase 2 (PDE2) regulates intracellular cyclic adenosine monophosphate and guanosine monophosphate (cAMP/cGMP) levels, which contribute to processes crucial for learning and memory. BI ...

The cyclic adenosine monophosphate–sensitive hyperpolarization–activated current ... DiFrancesco D, Tortora P. Direct activation of cardiac pacemaker channels by intracellular cyclic amp. Nature. 1991 ...