Low-sodium oxybate (Xywav) reduced blood pressure as expected compared with the higher-sodium version (Xyrem), reduced ...

The data gathered for several secondary and exploratory endpoints, including the Epworth Sleepiness Scale (ESS), Idiopathic Hypersomnia Severity Scale (IHSS) and Sleep Inertia Visual Analog Scale ...

Central hypersomnolence disorders, such as narcolepsy type 2 and idiopathic hypersomnia, are associated with reduced health-related quality of life.

It is also the only medicine approved for the treatment of both narcolepsy and another long-term sleep disorder called idiopathic ... symptoms on two scales. One was the IH Severity Scale, which ...

The INTUNE study included adults with idiopathic hypersomnia ... who had an Epworth Sleepiness Scale (ESS) score of at least 12 and a Patient Global Impression-Severity (PGI-S) score of moderate ...

The safety and tolerability profile of pitolisant in adult patients with idiopathic hypersomnia was consistent with the established safety profile and no new safety signals were observed.

Secondary endpoints of the Vibrance-3 study are changes in the Idiopathic Hypersomnia Severity Scale score and incidence of adverse events. Year to date, shares of Alkermes have gained 13.1% compared ...