Researchers have identified the human enzyme APEH as a crucial activator of antimalarial prodrugs, paving the way for more ...
This study demonstrates that the activities of soil extracellular enzymes were significantly altered in the alpine meadow, ...
between SOC and oxidase/hydrolase activity was found in the alpine meadow but not in the swamp meadow) between the two meadows. This indicates that carbon input and enzyme characteristics jointly ...
In this study, researchers found that a human enzyme, acylpeptide hydrolase (APEH), is the major activating enzyme of multiple antimalarial prodrugs known as lipophilic ester prodrugs. The APEH ...
BMS-986458 features three stereocenters, one of which epimerizes easily, Mortensen said. The drug candidate, which would be ...
In this study, researchers found that a human enzyme, acylpeptide hydrolase (APEH), is the major activating enzyme of multiple antimalarial prodrugs known as lipophilic ester prodrugs. The APEH ...
Audrey R. Odom-John, MD, PhD, senior study author, chief of the Division of Infectious Diseases at CHOP In this study, researchers found that a human enzyme, acylpeptide hydrolase (APEH), is the ...
In this study, researchers found that a human enzyme, acylpeptide hydrolase (APEH), is the major activating enzyme of multiple antimalarial prodrugs known as lipophilic ester prodrugs. The APEH ...
A popular experiment that's recommended to demonstrate the functionality of enzymes is chewing a piece of bread for a moment, then paying attention to when it turns from a starchy flavor to begin ...
Hydrolases are enzymes that catalyze the cleavage of a covalent bond using water. Types of hydrolase include esterases, such as phosphatases, that act on ester bonds, and proteases or peptidases ...