Histidine metabolism is rather complex; it is at the interface of many biosynthetic and metabolic reactions in the cell. It has profound effects on human physiology – from cognition to allergic ...

Writing in Nature, Kanarek et al. 1 report that degradation of the amino acid histidine can increase the sensitivity of cancer cells to methotrexate, and the results suggest that this approach can ...

Enzyme kinetic data from the BRENDA database were mapped onto the genome-scale metabolic model of Saccharomyces cerevisiae to ...

are now showing that the gut microbiota of people with treatment-naïve type 2 diabetes can be linked to a different metabolism of the amino acid histidine, which is mainly derived from the diet.