A new technical paper titled “Practical Guidance on Selecting Analytical Methods for PFAS in Semiconductor Manufacturing ...

Drug discovery can be a long and complex process. Medicines for neurodegenerative diseases like Alzheimer's disease are among ...

Figure 1. Concentration-response curves for the blockade of hERG channel current by (A) Phα1β and (B) dofetilide as assessed using a FLIPR ® potassium assay. HEK293 cells transfected with hERG were ...

Rationale:Genetic testing for Long QT Syndrome is now a standard and integral component of clinical cardiology. A major obstacle to the interpretation of genetic findings is the lack of robust ...

Firmenich International has patented a high-throughput assay system for identifying compounds that enhance olfactory receptor activity, intensifying the perception of target odorant compounds. The ...

High-throughput functional assays were validated using two classic atherosclerosis drugs, rosuvastatin and sirolimus, and were used to evaluate two drug candidates, curcumin and colchicine, and a ...

Metrion’s expanding portfolio of ion channel services now includes the new GLP hERG assays in addition to high throughput screening (HTS) in both automated electrophysiology and fluorescence ...

Metrion Biosciences Limited announced it has received notification from the UK’s Medicines and Healthcare products Regulatory Agency that the Company is now a member of the UK GLP Compliance ...

Study: High-Throughput CAMP Assay (HiTCA): A Novel Tool for Evaluating the Vitamin D-Dependent Antimicrobial Response.Image Credit: Iryna Imago/Shutterstock Background. Cathelicidins exhibit broad ...

There were 55 of 121 compounds that had low to very high hazard score in the CTCM assay, and only 5 of these 55 compounds (9%) showed no effect in the hERG assay, while 50 of 55 compounds (91%) were ...