To a molecular ... of biochemical data. We address this issue by describing the key findings in the evolution of our understanding of cooperative ligand binding by a single protein, hemoglobin ...

Hemoglobin has played a central role in the understanding of many biochemical and biophysical ... first genetic disease to be examined at the molecular level. The first documented case of sickle ...

Unexpected behavior has now been found in phthalocyanines, whose molecular ring structure closely resembles the crucial sections of hemoglobin or chlorophyll. Their center can be switched into ...

Biochemistry explores chemical processes related to living organisms. It is a laboratory-based science combining biology and chemistry. Biochemists study the structure, composition, and chemical ...

In a collaborative effort, researchers at the University of Amsterdam and the HFML-FELIX institute in Nijmegen have been able ...

Bizarre Scheme. Perutz studied molecular structure by analyzing X-ray photographs of crystallized hemoglobin. Scattered and deflected by the atoms within, the X-rays form a pattern of light and ...

In cells, respiration involves what are known as "respiratory proteins," e.g. hemoglobin in the blood ... in many respiratory proteins is a chemical structure called heme porphyrin.

New research has shown that the production of heme, a blood molecule, supports the progression of acute myeloid leukemia, which is an aggressive form of blood cancer. Researchers say that ...

Panel C shows the structure of the oxygen-binding pockets of the γ-globin subunits in persons with wild-type (left image) and mutant (right image) V67M deoxygenated hemoglobin F. The wild-type ...