Cytochrome c maturation and heme biosynthesis are central processes underpinning cellular respiration and energy conversion. In these pathways, heme – an iron‐containing porphyrin – is ...

As multiple companies vie to expand on Alnylam’s success in commercializing RNAi therapeutics, the pioneering company has set ...

Disc Medicine, Inc. (NASDAQ:IRON), a clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of novel treatments for patients suffering from serious ...

Award-winning research presented by Hangjie Fu at EHA shows that ellagic acid can protect against iron overload-induced liver ...

Positive updates across all programs, including longer term efficacy and safety data from the HELIOS open-label extension trial of bitopertin in erythropoietic protoporphyria (EPP), additional ...

Their biosynthesis, occurring predominantly in plastids ... In addition, research into heme-dependent cis–trans isomerases has uncovered novel enzymatic controls essential for the isomerisation ...

† † Vanderbilt Institute of Chemical Biology and ‡ Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States § Department of ...

(22) Little is known about RufO’s catalysis, including the substrate recognition mechanism, the changes at the catalytic site and overall protein structure in response to peptide binding, the ...

Heme biosynthesis is a very controlled process that occurs on every nucleated cell types, involving both mitochondrial and cytoplasmatic enzymatic pathways (Shemin 1989). The major part of all heme in ...

Please provide your email address to receive an email when new articles are posted on . Patients with stage III deficient mismatch repair colon cancer derived significant benefit from the addition ...

These data reflect BeiGene’s vision to redefine standards of care in hematology through next-generation science and patient-focused innovation. “With three cornerstone hematology assets ...

specially appointed lecturer in the department of respiratory medicine and hematology at Hyogo Medical University in Japan, said during his presentation. Clinical trials have found up to 10% of ...