Imidazoles and triazoles are essential chemical compounds used in many medicines, including drugs used to defeat various pathogen-induced infections and cancer. Besides these applications, both ...

The single glucose ring exists in three forms, α-glucose, β-glucose and α-glucose monohydrate. The detailed crystal structure of these compounds has already been given1–3.

In presynaptic nerve terminals, the endocytic apparatus rapidly restores synaptic vesicles after neurotransmitter release. Many endocytic proteins localize to the periactive zone, a loosely defined ...

Small molecule inhibitors restore normal BRAF structure, ... At the heart of this pathway, a protein called BRAF acts as a molecular switch that must be rigorously controlled.

Using cryo-electron microscopy, which enables visualization of frozen molecular structures at high resolution, the team analyzed this unique complex at a resolution of 3.66 Å (less than a ...

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The exception to this is small molecule crystal data, which must be deposited with the Cambridge Crystallographic Data Centre (CCDC). Choosing a repository The Royal Society of Chemistry supports the ...

At specific doses, NMN supplements may help improve insulin sensitivity and heart function and reduce tiredness with few side effects. But it’s a good idea to speak with a doctor before trying it.

This article reports a glucose sensor based on extended-gate amorphous indium gallium zinc oxide (a-IGZO) thin-film transistors (EG-TFTs) combined with microneedles (MNs) for diabetes detection. The ...

Phosphoglucose isomerase (PGI), which catalyzes the reversible interconversion of glucose 6-phosphate (G6P) and fructose 6-phosphate (F6P), is represented by two evolutionarily distinct protein ...