The structure of the ligand-binding domain of the glucocorticoid receptor has now been ... between RU24858 and conventional glucocorticoids by use of cell-based in vitro assays, ...

A recent study from the Institute of Biomedicine at the University of Eastern Finland shows that the glucocorticoid receptor ...

A recent study from the Institute of Biomedicine at the University of Eastern Finland shows that the glucocorticoid receptor ...

T-cell glucocorticoid receptor-deficient mice were generated using Lck promoter-driven, Cre recombinase-mediated excision of exon 2 of the glucocorticoid receptor gene.

Glucocorticoid receptors (GRs) are ligand-activated transcription factors that play a pivotal role in mediating the effects of endogenous and synthetic glucocorticoids.

TOPLINE: Relacorilant, a selective glucocorticoid receptor antagonist, combined with nab-paclitaxel significantly improved progression-free survival in women with platinum-resistant ovarian cancer.

Genomic assays play a critical role in guiding treatment decisions for patients with early-stage invasive breast cancer by providing prognostic and predictive insights. In a live Community Case Forum ...

A 34-year-old man was admitted to the hospital because of left ear pain with hearing loss and facial droop on the left side. Computed tomography showed a nasopharyngeal mass. A diagnosis was made.

The nuclear constitutive androstane receptor (CAR, NR1I3) plays significant roles in many hepatic functions, such as fatty acid oxidation, biotransformation, liver regeneration, as well as clearance ...

Understanding potential health risks is a significant challenge due to the large numbers of diverse chemicals with poorly characterized exposures and mechanisms of toxicities. The present study ...