The newest assay kit, launched in August ... human estrogen receptors, liver X receptors, glucocorticoid receptor, farnesoid receptor, and mineralocorticoid receptor. Kits are also available ...

In addition, the assay format could be applied to other nuclear receptors to allow monitoring for compounds with androgen-, glucocorticoid-, or progesterone-like activity, which, as yet ...

INTRODUCTION: Ineffective response to glucocorticoids (GCs) in severe asthma may result from enhanced T‑cell activation, immune dysregulation, or altered expression of glucocorticoid receptor (GR ...

How do activation of glucocorticoid receptor-deficient T-cells and dysregulation of COX-2 activity cause mortality? Histological analyses of TGRKO and control mice treated with antibody to CD3ε ...

In prostate cancer, the glucocorticoid receptor can replace the activity of the androgen receptor, which is main oncogenic factor in this cancer, when its activity is inhibited by drug therapy.

Inflammation is a reflexive response to infection, the binding of antibodies to antigens within the body, mechanical irritation, or injury. 1 Microbes that breach epithelial barriers, for instance ...

Expression and nuclear translocation of glucocorticoid receptors in type 2 taste receptor cells. Neuroscience Letters , 2014; 571: 72 DOI: 10.1016/j.neulet.2014.04.047 Cite This Page : ...

ABBV-154, an antibody-drug conjugate comprising adalimumab conjugated to a proprietary glucocorticoid receptor modulator, shows potential for extending flare-free periods in patients with ...

Researchers examine the mechanisms by which glucocorticoid receptor activity, which varies by time of day, modulates tumor progression and how targeting circadian-driven tumor behaviors could be ...