Oxford, UK - 5 February 2025: OXB (LSE: OXB), a quality and innovation-led cell and gene therapy CDMO, today announces the ...
Intraperitoneal delivery of adenoviral gene therapy in vivo is safe and nontoxic. The use of new diluents, already used in peritoneal renal dialysis, will improve drug delivery, reduce therapeutic ...
Adenoviral vectors are increasingly recognized as powerful tools in gene therapy and vaccine development. These vectors, derived from adenoviruses, can deliver genetic material into cells, making ...
Researchers have demonstrated, for the first time in the world using mice, the ability to overcome significant challenges in ...
Adenoviruses (Ad) are currently the most commonly used vectors in gene therapy clinical ... efficacy of the vector and causes toxic side effects. The 46 kDa coxsackie and adenovirus receptor ...
Exposing Adenoviruses: Inder Verma and colleagues used nude mice to study immune system and humoral responses during gene therapy ... immune responses to adenoviral vectors containing factor IX gene: ...
In two new papers, researchers from The Jackson Laboratory (JAX) report the successful use of two approaches—gene therapy and ...
The companies will work together by using the codon-optimized BBS1 AAV9 vector to minimize the vision loss caused by the ...
For recurrent respiratory papillomatosis (RRP), novel gene therapy to jump-start immunity to the human papillomavirus (HPV) ...
Researchers are enhancing the best features of AAV capsids and overcoming their limitations to accelerate gene-based therapies.