Why retinoic acid is effective in this setting but not against primary tumors, has been speculated about for nearly 50 years. Scientists resolved the mystery, showing the drug 'hijacks' a normal ...

Neuroblastoma is a solid tumor that occurs in children. When high-risk, the disease has a poor prognosis. Decades ago, adding ...

Launched Niktimvo in the U.S. in late January, in partnership with Incyte. Niktimvo is approved by the U.S. FDA for the treatment of chronic graft-versus-host disease (GVHD) after failure of at least ...

The long-term survival of a patient with neuroblastoma suggests the personalized cancer treatment may work for solid tumors, not just blood cancers.

The lab of Filippo Veglia, Ph.D., at The Wistar Institute has discovered a previously unknown mechanism for how aggressive ...

A research team has elucidated the mechanism behind bacterial cancer therapy using a genetically engineered bacterial strain.

For decades, scientists have explored the potential of bacteria in fighting cancer, but safety and efficacy barriers have ...

From the approval of the first immune checkpoint inhibitors to the development of chimeric antigen receptor T cells, immunotherapy has demonstrated ...