As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

The following sections are devoted to provide detailed examples of these novel chemistries and are organized according to the overall reaction types catalyzed including cyclopropanation, ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Electrochemically driven organic reactions present an appealing alternative to ...

Cell culture and in vitro transmigration assay Caco-2 human intestinal epithelial cells were cultured and polymorphonuclear (PMN) cell transmigration towards a gradient of 100 nM ...

The effects of RvD1 in promoting IL-10 production were also inhibited by N-formyl peptide receptor 2 (FPR2) antagonist. The primary cultured DRG neurons apoptosis increased after stimulation with ...

Sepsis is a life-threatening clinical syndrome characterized by multiorgan dysfunction caused by a dysregulated or over-reactive host response to infection. During sepsis, the coagulation cascade is ...

Detecting danger is key to the survival and success of all species. Animal nervous and immune systems cooperate to optimize danger detection. Preceding studies have highlighted the benefits of ...

The desired products can be purified in subsequent steps, for example with Streptavidin columns to remove unconjugated antibodies, or with size exclusion columns, to separate HC 2 LC 2 from other ...