infusion over 30 min Actinomycin D 0.5 mg iv. bolus Folinic acid rescue 15 mg orally every 12 h for four doses (starting 24 h after commencing the methotrexate infusion) For patients with brain ...

Pyrimethamine, sulfadiazine and folinic acid should be administered to mothers whose seroconversion is suspected or confirmed to have occurred after 18 weeks of gestation, mothers with positive AF ...