Plants synthesize an extensive array of secondary metabolites in response to diverse biotic and abiotic stresses. These metabolites function not only as defensive compounds but also constitute ...

"The latest findings for our next-generation farnesyl transferase inhibitor, KO-2806, being presented at this year's AACR Annual Meeting, add to the growing body of data demonstrating the potential of ...

The presentation, scheduled for April 28, 2025, will detail findings on the use of KO-2806, a farnesyl transferase inhibitor, in combination with cabozantinib, a tyrosine kinase inhibitor ...

SAN DIEGO and TOKYO, April 08, 2025 (GLOBE NEWSWIRE) -- Kura Oncology, Inc. (Nasdaq: KURA, “Kura”), and Kyowa Kirin Co., Ltd. (TSE: 4151, “Kyowa Kirin ...

When your body uses ATP for energy, it loses a phosphate group and becomes adenosine diphosphate. Therefore, when your body needs a quick source of energy, creatine lends its phosphate to ADP and ...

In addition, the diterpene synthase PvHVS also accepts an ether derivative of farnesyl pyrophosphate and converts it to the same tetrahydrofuran core as found for the analogous extended GGPP substrate ...

where it is broken down and turned into ADP (adenosine diphosphate). This is where creatine can help by regenerating ATP within the muscles, allowing you to sustain high-intensity performance for ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. In order to increase activity and affinity of PKT on the ...

From Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville Campus, Victoria, Australia (R.H.R.) Division of Endocrinology and Metabolism (E.D.A.), ...