Large-scale comparison of gene families across 1154 Saccharomycotina genomes revealed that gene gains and losses drive yeast ...

Figure 1: Domain organization of classical HDACs from yeast and humans ... would it be more reasonable to target the signalling pathways that control HDAC functions? Each HDAC has multiple ...

A set of linear pathways often does not capture the full range of behaviors of a metabolic network. The concept of ‘elementary flux modes’ provides a mathematical tool to define and ...