The first step in V(D)J recombination is site recognition and cleavage. The V(D)J recombinase creates a synaptic complex with two recombination signal sequences (RSSs), nicks the DNA between the ...

Loss of MCUB subunit results in an expansion and greater interconnection of the MCU protein network. Tandem affinity purifications (TAPs) from Flp-In T-REx HEK293 cells that are wild-type (Ctrl) or ...