A team of investigators from Dana-Farber Cancer Institute, The Broad Institute of MIT and Harvard, Google, and Columbia University have created an artificial intelligence model that can predict which ...

Ubiquitylation is a reversible post-translational modification involved in a myriad of cellular functions. A superfamily of approximately 100 ubiquitin-specific proteases, called deubiquitylating ...

The course focuses on current understanding of the structure and function of eukaryotic transcription factors. The aim of the first general part is to give the student an understanding of the main ...

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Recently, mtDNA has been shown to have some covalent modifications such as methylation or hydroxylmethylation, which play pivotal epigenetic roles in mtDNA replication and transcription ...

For example, the ability of a single transcription factor to bind a response element might depend on the presence of other transcription factors and their ligands, on components involved in ...

In 1989 he founded and became the director of the Insitut Pasteur’s Molecular Microbial Pathogenesis Unit. He is Professor of Microbiology and Infectious Diseases at the Collège de France. He has ...