The eukaryotic DNA sliding clamp that keeps DNA polymerase engaged at a replication fork, called proliferating cell nuclear antigen (PCNA), is loaded onto the 3′ ends of primer DNA through its ...

Myers, T.W. & Gelfand, D.H. Reverse transcription and DNA amplification by a Thermus thermophilus DNA polymerase. Biochemistry 30 , 7661–7666 (1991). Article CAS Google Scholar ...

This valuable manuscript investigates the localisation of nutrient receptors in bloodstream stage trypanosomes, with implications for both nutrient uptake and immune evasion. Results after direct ...

In 1992, investigators working on mixing and fusing various domains of different DNA polymerases showed that, when combined with the robust reliability of Taq DNA polymerase, these enzymes ...

How do cells precisely turn genes on and off? New research on yeast reveals a protein's DNA binding strength and location ...

High fidelity human mitochondrial DNA polymerase (Pol γ) contains two active sites, a DNA polymerization site (pol) and a 3′-5′ exonuclease site (exo) for proofreading. Although separated by 35 Å, ...