Enzyme-catalysed reactions require the specific interaction between the enzyme and its substrate in the Michaelis complex. Due to turnover, Michaelis complexes are typically transient making them ...

Using artificial intelligence, researchers show how γ-secretase recognizes substrates - an important advance for fundamental ...

There are two theories explaining the enzyme-substrate interaction. In the lock-and-key model, the active site of an enzyme is precisely shaped to hold specific substrates.

Researchers from DZNE, Ludwig-Maximilians-Universität München (LMU), and Technical University of Munich (TUM) have found that ...

Grapefruit juice is more than a breakfast staple—it’s a potent enzyme inhibitor that can dramatically alter how certain drugs are metabolized. This article explores how a tiny structural difference ...

It is thought that the inactivation is due to a specific enzyme–substrate interaction that breaks at around room temperature. Using computer simulations of a catalyzed chemical reaction, the ...

Glycans are chains of sugars that attach to cells through proteins or lipids, changing their chemical characteristics.

Antioxidant-enzyme Interaction in non-communicable diseases. Xia & He Publishing Inc. Journal Journal of Exploratory Research in Pharmacology DOI 10.14218/JERP.2024.00020 ...