Considering the geometry of such an enzyme-substrate-complex, they identified three golden rules that should be considered to build a functional enzyme. First, the interface of both enzyme and ...

The molecules that form the foundation of life on Earth are as diverse as they are complex. Among these, carbohydrates play a ...

Figure 5: Standard view from the μPl substrate towards the active site of the μPl enzyme in complex with SAK (shown as a solid surface). The overall structure of the cleaved μPl substrate is ...

Views diverge on what protonation state is characteristic of catalytic Cys and His at the Michaelis (enzyme–substrate) complex of TEVp and related proteases. (23) It is not a cosmetic difference, ...

Using E. coli and plastic waste to produce a common pain medication, researchers say their findings could pave the way for ...

Background IVD is a key enzyme in leucine catabolism, catalyzing the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA.

BackgroundIVD is a key enzyme in leucine catabolism, catalyzing the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA. Defects in IVD function lead ...

Researchers have revealed the molecular details behind how vitamin K's membrane enzyme, vitamin K-dependent gamma carboxylase ...

Researchers uncover how key enzymes team up to break down proteins, offering new insight into diseases like Alzheimer’s and certain cancers tied to protein mismanagement.