Researchers have discovered that an enzyme can serve as an ideal target for developing new therapeutics against Lyme disease, ...

Oxygenases have long been thought to require a cofactor for catalysis. The structure of a vancomycin biosynthetic enzyme in complex with a substrate analog, and with molecular oxygen bound in its ...

Notably, the engineered enzyme did not require any cofactors for conversion, unlike other oxidases, and produced vanillin on a gram scale per liter of reaction solution, with a higher catalytic ...

Sulfur is also less electronegative than oxygen, permitting it to more readily adopt a positive charge, which is used by a number of enzyme cofactors. S-adenosylmethionine (SAM or AdoMet), which ...

A team of scientists has zeroed in on an enzyme that could revolutionize Lyme disease treatment. By uncovering the crucial ...

The Stull lab primarily focuses on the class of enzymes that use riboflavin-derived cofactors (flavin-dependent enzymes), which catalyze a wide array of chemical transformations that are crucial for ...

ST. LOUIS--(BUSINESS WIRE)--Cofactor Genomics announced today OncoPrism for colorectal, breast, bladder, and kidney cancer. This announcement follows recent Medicare coverage of the OncoPrism ...

Sapropterin dihydrochloride 100mg; per pkt; pwd for oral soln. Javygtor is a synthetic form of BH4, the cofactor for the enzyme phenylalanine hydroxylase (PAH). PAH hydroxylates Phe through an ...