Pancreatic cancer is a leading cause of cancer-related death, with a five-year survival rate of 13%. The high mortality is ...

Scientists created ‘venom maps’ to predict Russell’s viper venom profiles, which could help clinicians tailor efficient ...

but this is the first to examine the role of the enzyme in aging immune cells. When the genetically altered mice were just 18-20 months old, the lack of ELOVL2 enzymatic activity decreased the ...

Research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...

New research reveals that the enzyme HDAC5 plays a critical role in suppressing a gene (Scn4b) that regulates brain activity associated with drug-related memories, which are central to relapse in ...

Key Laboratory of Quality and Safety Control of Citrus Fruits, Ministry of Agriculture and Rural Affairs, Southwest University, Chongqing 400712, P.R. China National Citrus Engineering Research Center ...

Previous studies have shown that severe variants exhibit lower GCase activity levels and demonstrate a more significant decline over time during follow-up (3, 4). The diagnostic accuracy of the 4-MUG ...

They determined the crystal structures of two such enzymes, conducted in vitro enzyme activity assays, and a thorough structure-guided mutagenesis campaign to interrogate the role of specific residues ...

This useful manuscript reports on the crystal structures of two glycosaminoglycan (GAG) lyases from the PL35 family, along with in vitro enzyme activity assays and comprehensive structure-guided ...

Key Laboratory of Analytical Science for Food Safety and Biology (MOE & Fujian Province), Department of Chemistry, Fuzhou University, Fuzhou 350108, People’s Republic of China ...