News

Q&A: How parasites—and a bit of serendipity—led to a powerful new drug discovery tool
From cancer to infectious diseases to neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, there ...
Glowing biosensor streamlines high-throughput drug screening
Drug discovery can be a long and complex process. Medicines for neurodegenerative diseases like Alzheimer's disease are among ...
Mirage News11h
Prof. Kang's Team Unveils AICAR Biosynthesis in F. Solani
Prediction of key genes in the AICAR biosynthetic pathway of endophytic Fusarium solaniPrevious study showed that overexpression of the global ...
eLife23h
HIV-specific CD8+ T-cell responses soon after treatment initiation during acute HIV infection are associated with viral reservoir decline
Antiretroviral therapy (ART) initiated in the acute phase of HIV infection (AHI) results in a smaller viral reservoir. However, the impact of early HIV-specific T-cell responses on long-term reservoir ...
eLife23h
Deployment of endocytic machinery to periactive zones of nerve terminals is independent of active zone assembly and evoked release
In presynaptic nerve terminals, the endocytic apparatus rapidly restores synaptic vesicles after neurotransmitter release. Many endocytic proteins localize to the periactive zone, a loosely defined ...
Hospital Healthcare Europe14h
In vitro advances in predicting resistance to PARP inhibitors for BRCA1/2 mutations
Drs Olga Brieieva and Martin Higgs discuss in vitro genomic models for predicting clinical resistance to PARP inhibitors for ...