(3, 4) Consequently, the identification of novel compounds that ameliorate ER stress and reduce cellular apoptosis may have clinical relevance for the treatment of numerous disease states. The ER is ...

When the workload on the heart increases, the ventricular wall may thicken too, known as cardiac hypertrophy. This is an adaptive response that reduces pressure on the heart and maintains the activity ...

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SGLT2 (sodium-glucose cotransporter 2) inhibitors produce a distinctive pattern of benefits on the evolution and progression of cardiomyopathy and nephropathy, which is characterized by a reduction in ...

A new study in Small presents a nanoparticle-based delivery system combining CuET and BIO for treating resistant melanoma, ...

The mitochondria and the endoplasmic reticulum (ER) are two organelles that critically contribute to apoptosis induction. While it is established that they communicate, how cell death signals are ...

Numerous inflammatory cytokines have been implicated in the pathogenesis of cardiovascular diseases. Monocyte chemoattractant protein (MCP)-1/CCL2 is expressed by mainly inflammatory cells and stromal ...

The Stress Factory LLC is off Apperson Drive. It’s not your typical stress-relief spot. Owner Eddie Day calls it a decompression center, designed to help you let you the built-up anxiety and ...

Ulcerative colitis (UC) is a chronic inflammatory bowel disorder distinguished by alternating phases of remission and exacerbation. Restoring immune balance through the modulation of M1 macrophage ...