New research reveals that the enzyme HDAC5 plays a critical role in suppressing a gene (Scn4b) that regulates brain activity associated with drug-related memories, which are central to relapse in ...

Proper digestion prevents undigested food from accumulating in the intestines, which can disrupt the gut microbiome and lead to digestive disorders. Enzymes like cellulase break down plant fibres ...

COLUMBUS, Ohio – Researchers have found that targeting an enzyme called PGM3 can help stop the growth of glioblastoma, the ...

Most people with inherited metabolic disorders have a defective gene that results in lack of an enzyme. According to the latest count, 1,564 of these disorders have been identified. There are ...

Researchers at the University of Gothenburg have identified a small molecule, PZL-A, that restores function in the defective ...

The biotech is developing an experimental drug for the most common of a family of disorders all caused by errors in ...

A fundraiser to benefit brave 4-year-old township resident Scarlett Griffith and heighten awareness about the rare genetic ...

neurodegenerative disorders like Parkinson's disease, and other serious illnesses. Now, a new study demonstrates a proof of concept for a new strategy: engineering proteases -- enzymes that cut ...

Past attempts to evolve proteases for therapeutic use have resulted in enzymes that targeted too ... role in Parkinson's disease and related disorders, it was used in this study as a model protein ...

Research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...

Learn how metabolic disorders are detected and diagnosed with Dr. Irene De Biase, professor of clinical pathology at the ...