In this video, Xiuning Le, MD, PhD, discusses how the definition of EGFR-mutated lung cancer has expanded in recent years.

Monoallelic loss of PTEN and ARID1A is identified in normal colonic epithelium. The resulting haploinsufficient phenotypes ...

Blood does more than just carry oxygen and nutrients. Its many “markers,” known as antigens, can trigger unexpected responses. Most folks have heard about the blood groups A, B, and O, and the Rh ...

Video: Broad Institute of MIT and Harvard At a glance: Study explains long-standing question of why Huntington’s disease symptoms typically do not appear until midlife even though patients are born ...

For their definition, the group focused on adiposity, the amount of fat stored in the body, and how it affected organs and tissue. “We define clinical obesity as a chronic, systemic illness ...

This means that the damage has multiple chances to generate harmful mutations, which can lead to cancer. While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms ...

The Garvan team revealed that this is not the case -- rather, the critical trigger is mutations in 'rogue clone' B cells. "This discovery fundamentally changes our understanding of how infections ...

A global commission of experts has called for a radical shift in how obesity is diagnosed, with less reliance on body mass index (BMI) to define disease. The commission, published in Lancet Diabetes ...

The goal of the Lancet Diabetes & Endocrinology Commission on the Definition and Diagnosis of Clinical Obesity was to develop an approach to this definition and diagnosis. The commission ...

In early December 2024, a group of researchers published an article in the journal Science, entitled "A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors".