DNA polymerase (DNAP) is a type of enzyme that is responsible for forming new copies of DNA, in the form of nucleic acid molecules. Nucleic acids are polymers, which are large molecules made up of ...

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional ...

RNA polymerase is an enzyme that is responsible for copying a DNA sequence into an RNA sequence, duyring the process of transcription. As complex molecule composed of protein subunits, RNA ...

How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...

DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...

Several components are involved in a PCR including template DNA, forward and reverse primers, DNA polymerase enzyme, and reaction buffer. Scientists must ensure that all reagents in the reaction are ...

If your genes could set an alarm clock, EZH1 might be the one ringing the bell. A new study has revealed how this ...

The double helix unwinds, and each strand serves as a template for the synthesis of a new complementary strand. DNA polymerase enzymes facilitate this process, ensuring accurate copying of the genetic ...

where the enzyme DNA polymerase zips along the single strands starting at the primer to replicate the DNA. The cycle repeats and copies of the original DNA accumulate exponentially. Like any ...

the Klenow polymerase the scientists were using was problematic. It degraded at 94°C, the temperature required to denature the DNA target; this meant that the scientists had to open the PCR reaction ...

The genetic connections between DNA repair pathways and human cancer predisposition have fueled interest in the proteins that recognize and repair specific sites of DNA damage. The repair enzymes are ...

Enzymes called RNA polymerases transcribe DNA into RNA. RNA is the intermediary that carries ... types of RNA polymerases that can transcribe different types of RNA. RNA polymerase II, shown here, is ...