The superfamily 1 (SF1) and SF2 enzymes are non-hexameric enzymes possessing both helicase and single-stranded DNA (ssDNA) translocase activities, as well as the ability to displace proteins from DNA.

To our knowledge, there are no existing investigations employing a separation protocol resembling the helicase dissociation process of DNA. Helicases break hydrogen bridges in a helicoidal-sequence ...

Researchers at The University of Hong Kong (HKU) have made an exciting discovery about how human cells protect DNA during ...

Browse 30+ helicase stock illustrations and vector graphics available royalty-free, or search for dna replication to find more great stock images and vector art. DNA replication. Steps. double helix ...

How does the cell protect these strands from damage? How would you identify the protein that serves as a connector between DNA helicase and pol-a/primase? A simple yet often effective approach is ...

During DNA licensing, multiple proteins assemble and function to load an enzyme called DNA helicase onto the DNA. This acts as a kind of molecular ‘flag’ that the DNA is ready for replication. The ...

At the interface of repair with transcription and replication, helicase–nuclease–RPA partnerships have major roles in genome maintenance by directional unwinding and processing structured nucleic ...

The small molecule works by inhibiting ALC1 (chromodomain-helicase-DNA-binding protein 1-like), a chromatin remodeller and DNA helicase also involved in DNA repair. In what Schomburg terms a ...

in controlling fork progression and origin activation by inhibiting the activities of the replicative DNA helicase, CMG (Cdc45-MCM-GINS), and the cell cycle-regulated protein kinase, DDK ...

In this study, the researchers report that VGLL3 can be recruited to DSBs in a PARylation- and chromodomain helicase ...

Researchers have made an exciting discovery about how human cells protect DNA during cell division, offering new insights into combating diseases such as cancer. The research uncovers the vital role ...

We were able to load a human exosome with an optimized DNA-RNA chimera that stalls the MTR4 helicase during unwinding and determined its structure by single particle cryoelectron microscopy (cryo-EM) ...