Therefore, chromatin is further coiled into an ... the packing ratio of DNA in metaphase chromosomes is approximately 10,000:1 (depending on the chromosome). This can be thought of as akin to ...

It must be compatible with the high concentration of DNA and the elongated cylindrical shape of chromosomes and the known self-associative properties of chromatin, and also with an effective ...

Chromosomes also play a role in regulating gene expression. The structure and packaging of chromatin can influence which genes are active or silenced in a particular cell type or developmental stage.

Zhang and his colleagues designed a generative AI model called ChromoGen to quickly ‘read’ DNA sequences and predict the ...

Northwestern Medicine scientists have discovered new details about how the human genome produces instructions for creating proteins and cells, the building blocks of life, according to a pioneering ...

Worldwide, hepatitis B is thought to be the second deadliest infection; about 5% of the global population are infection and ...

Each cell of the human body contains two meters of DNA ... we look at the average chromatin structures in human cells and many other organisms, we will see that chromosomes seem to be folded ...

The parasite that causes malaria requires precise control of gene expression to progress through the various stages of its ...

"We were delighted to discover not only important details about the mechanisms of HBV gene regulation, but also a promising ...

A new study has unveiled the intricate 3D genome structure of Brassica crops, thanks to an optimized Bridge Linker ...