Conclusion Broadening the HDA population to include either low complement or positive anti-dsDNA, rather than both, would enable more UK patients to receive SLE treatment and experience improved ...

Despite anti-dsDNA antibodies constitute a wide range of specificities, they are considered as the hallmark for systemic lupus erythematosus (SLE). Objective To identify clinical phenotypes associated ...

We introduce MADna, a sequence-dependent coarse-grained model of double-stranded DNA (dsDNA), where each nucleotide is described by three beads localized at the sugar, at the base moiety, and at the ...

This valuable study focuses on defining how the HSP70 chaperone system utilizes J-domain proteins to regulate the heat shock response-associated transcription factor HSF1. Using a combination of ...

Few would have been surprised if Cyndi Lauper had entered the Rock & Roll Hall of Fame during her first year of eligibility back in 2008. After all, she’s one of the most successful artists of ...

From folk hero at Arizona State to rookie in the Big Apple, Cam Skattebo is ready to prove himself all over again. A fifth-place finisher in Heisman Trophy voting last season, Skattebo is fresh ...