Homeostasis is the ability of living organisms to maintain stable internal conditions, such as temperature, hydration and ...

Recent technological advances are fueling the development of cutting-edge technologies that can monitor and control ...

Taste, pain, or response to stress—nearly all essential functions in the human body are regulated by molecular switches ...

This valuable study focuses on defining how the HSP70 chaperone system utilizes J-domain proteins to regulate the heat shock response-associated transcription factor HSF1. Using a combination of ...

Several human pathogens exploit the kinetic forces generated by polymerizing actin to power their intracellular motility. Human cell-autonomous immune responses activate ...

Researchers found that inhibiting GSK-3 led to less defects in the axonal transport process and less neuronal cell death, while inhibiting ERK1 led to more transport problems and more cell death.

After you eat a meal, zinc is taken up by the cells of your body. Inside each cell, zinc binds to proteins to support their structure and function. Researchers estimate that up to 10% of all proteins ...

Polyethylenimine (PEI) polymers are used to compact DNA into nanoparticles for delivery into cells. We have shown that PEI-mannose polymers compact DNA into nanoshell-like particles, which can load ...

Institute of Materials Science and Engineering, École polytechnique fédérale de Lausanne, Lausanne 1015, Switzerland Institute of Bioengineering, École polytechnique fédérale de Lausanne, Lausanne ...

While a comprehensive cure-all to these neurological conditions is unlikely, scientists are making headway into understanding their fundamental characteristics with the hope of preventing or ...

"Through both in vitro and in vivo trials, we found that boosting ATP production decreases cytosolic viscosity in affected cells, dispersing existing and preventing future pathological protein ...

"Mammalian cells normally have an average ... boosting ATP production using NMN rescued cytosolic fluidity by breaking up and solubilizing existing protein aggregates in axons from ALS neurons.